Cryogenic micronization is a specialised process that achieves optimal material reduction at low temperatures, typically utilising liquid nitrogen. This method involves cooling both the product and the micronization chamber, thereby maintaining consistently low gas temperatures.
The result is a controlled and highly effective micronization process that safeguards material integrity. Operating at these low temperatures critically limits the formation of amorphous particles, prevents polymorphic changes, minimises impurity increases, and significantly reduces the re-agglomeration of micronized particles.
Munit offers GMP-compliant cryogenic setups, meticulously designed to guarantee precise scalability and maintain the highest standards across the pharmaceutical, chemical, and food sectors.