Handling high potency APIs (HPAPIs), cytotoxic materials, and other sensitive compounds requires absolute control. At Munit, we specialize in high containment milling using isolator-based systems that ensure both operator safety and product integrity.
What Is High Containment Milling?
High containment milling involves particle size reduction performed inside fully sealed, pressurized isolators. These systems prevent airborne contamination and product loss, especially critical for HPAPIs with low Occupational Exposure Limits (OELs). Our systems meet OEB 4–5 containment standards, enabling safe handling of even the most potent compounds.
Munit’s Isolator-Based Jet Milling Systems
Our proprietary spiral jet mills are fully integrated into isolators. Each unit is designed for inert processing, with HEPA filtration and validated cleaning protocols. We support both clinical and commercial production under GMP, offering flexibility and batch-specific setups for maximum safety.
Applications for HPAPI and Cytotoxic Processing
We support a wide range of high-risk pharmaceutical substances, including oncology APIs, hormones, and immunosuppressants. Our containment systems are ideal for dry powder processing, nitrogen milling, and compounds requiring enhanced operator protection.
Regulatory and Safety Advantages
All containment processes are performed under full GMP, with real-time monitoring, OEL testing, and traceable batch records. Our internal protocols are aligned with global regulatory frameworks and designed to pass the most rigorous audits.
Looking for secure HPAPI processing?
Get in touch with Munit’s containment experts.