While jet milling provides ultra-fine particle sizes, many pharmaceutical projects benefit from mechanical milling for pre-processing, deagglomeration, or coarse reduction. Munit offers GMP-compliant mechanical milling services using various mill types.

Applications of Mechanical Milling

Mechanical milling is suitable for:

• Coarse particle size adjustment before micronization
• Crystalline API stabilization
• Excipient and bulk powder processing
• Moisture-sensitive material preparation

This is often a first step before fine jet milling or as a standalone process for certain formulations.

Milling Equipment and Options

We use:

• Pin mills for intermediate grinding
• Hammer mills for coarse reduction
• Impact mills for high-speed processing

Mills are installed in GMP cleanrooms and operated under validated cleaning and calibration procedures.

Documentation and Quality Control

Each batch includes:

• Executed batch records
• In-process control results
• PSD and moisture analysis
• Cleaning validation

We ensure full compliance with pharmaceutical GMP standards.

Need flexible size reduction beyond micronization?
Explore mechanical milling options at Munit.