Optimized Co-micronization Method: Efficient Manufacturing
Co-micronization is a cost-effective method of micronizing two substances simultaneously. Typically, co-micronization involves micronizing one API and one excipient, although it could also be one API and two excipients or two APIs and one excipient.
The excipient is typically added in lower amounts to improve the mechanical properties of the API, which is the main component of the mixture. Traditionally, manufacturers blend the elements of the final mix in advance and then micronize the blended powder to the final PSD specification. However, this approach involves at least two separate steps - blending and micronization.
Our innovative co-micronization approach combines blending and micronization into a single step to improve homogeneity, reduce time, and lower costs. By homogeneously feeding the right proportions of two or three powders into the Spiral Jet mill, our approach simplifies the manufacturing process, making it more efficient and effective.
